Research into conolidine has brought about discovery of the opioid receptor in the body referred to as ACKR3/CXCR7. ACKR3 is apparently probably the most sought after focus on for conolidine, which also disregards another 4 classical opioid receptors(three). thank you.. A: There is limited facts on contraindications involving Conolidine https://www.proleviate.com/post/conolidine-an-alternative-natural-pain-relief-to-replace-traditional-painkillers