Poor/Comprehensive Metabolizers, CYP2D6 The formation with the active metabolite, M1, is mediated by CYP2D6, a polymorphic enzyme. Around 7% on the population has lessened exercise of your CYP2D6 isoenzyme of cytochrome P450 metabolizing enzyme technique. These individuals are “poor metabolizers” of debrisoquine, dextromethorphan and tricyclic antidepressants, between other medication... https://taylorq986xch0.vblogetin.com/profile