Nonetheless, a similar focus of Earn but not other CB1R agonists, boosts intracellular Ca2+ concentration by means of Gq/11 protein in transfected HEK-293 cells and cultured hippocampal neurons with endogenous receptor expression [ninety three]. What's more, in mice hippocampal slices, CB1R expressed in astrocytes is coupled to Gq/11, increases intracellular https://simonzpesh.uzblog.net/not-known-factual-statements-about-cannabinoids-46949746